What is microsatellite instability

Microsatellite instability is a specific form of genomic instability that is characterized by mutational alteration of simple repetitive sequences, including both expansions. Microsatellite instability in colorectal cancer Mar 1 20Keywords: colorectal cancer, microsatellite instability, chemotherapy. Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of. Microsatellite Instability in Colorectal Cancer Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatch repair activity.

Jan 1 20The instability of one site is called low microsatellite instability (MSI-L and the instability of two or more sites is called high microsatellite instability (MSI-H). MSI is detected in about of all colorectal cancers are of these are associated with.

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Microsatellite Instability in Colorectal Cancer

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