What is parp

DNA damage may be caused by normal cell actions, UV light, some anticancer drugs, and radiation used to. DNA damage may be caused by many things, including exposure to UV light, radiation. They block so-called PARP proteins in the body that fix mutated cancer cells and help them to.

PARP Inhibitors Targeted cancer drugs Cancer Research UK PARP Inhibitors in Combination. PARP inhibitor - A substance that blocks an enzyme in cells called PARP.

PARP Inhibitors Targeted cancer drugs Cancer Research UK

PARP A type of enzyme involved in many functions of the cell, including the repair of DNA damage. A new class of drugs called PARP inhibitors can stop some of the harmful effects of BRCA mutations. Any of a group of enzymes (five have been identifiedPARP 15) whose prototypic member (PARP 1) is encoded by PARP on chromosome 1q41-q42. Following the expanded clinical use of PARP inhibitors and the high likelihood of acquired resistance, there is a significant need for clinical strategies combining PARP.

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Definition of PARP - NCI Dictionary of Cancer Terms

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